The data coming out of ASCO 2012 for Zytiga is not good. Early use of Zytiga was no better than placebo for 18 months. The Kaplan-Meier curves for Zytiga show that there was no survival trend seen until 18 months after the 14 month long treatment began.
That is, the placebo group and Zytiga group were basically the same in terms of deaths for 18 months.
Zytiga is not doing any good for you folks using it for early / off label use.
Don't believe the hype given by the news press. Go directly to the trial data.