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Pancreatic Neuroendocrine Tumor (PNET)

Pancreatic neuroendocrine tumor (PNET) support group and discussion community

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Pancreatic Neuroendocrine Tumor (PNET)

New Feature - Inspire Reactions

ErikInspire's journal

ErikInspire

new-feature-inspire-reactions

200232

Earlier this year, we had a wonderful discussion with all of you about Facebook-style “Like” buttons on Inspire, and all of the positives and negatives that are associated with them. Through more than 200 replies we heard from many of you with widely differing opinions. The overwhelming consensus was that, while the idea of being able to give reactions to posts and comments could be ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

PD1/PD-L1 is the superstar checkpoint

fighterm's journal

fighterm

pd1-pd-l1-is-the-superstar-checkpoint

200232

1980s and 90s were full of discoveries of immune checkpoints and immune costimulators. Due to that pioneering research of doctors and scientists we now have our new immunotherapy. (Took almost 25 years from the lab studies to clinic). Some of the study titles done at that time: 1. LAG-3, a novel lymphocyte activation gene closely related to CD4. 1990. 2. Induced expression of PD-1 ... Read More

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Pancreatic Neuroendocrine Tumor (PNET)

How do T cells work to fight cancer?

fighterm's journal

fighterm

how-do-t-cells-work-to-fught-cancer

200232

Every cell in our body has MHC (Major Histocompatibility Complex) that is located on the cell surface. If there are mutated peptides (neoantigens) inside a cell they are transported into the MHC for immune cells to see them. That is how T cells can see cancer. By the late 1980s, it was known that simple engagement of T cell antigen receptors (TCRs) and the MHC holding a neoantigen ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

What not to say to a cancer patient

Cancer-Inspire's journal

Cancer-Inspire

what-not-to-say-to-a-cancer-patient

200232

By Radha_Inspire Digital Editor, Inspire A Personal Health column at the New York Times today discussed what to say and, crucially, what not to say, to cancer patients based on a book called Loving, Supporting and Caring for the Cancer Patient by Dr. Stan Goldberg, a prostate cancer patient and communications specialist at San Francisco State University. Any type of discussion about ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

How do you make medical decisions?

Brian's journal

Brian

how-do-you-make-medical-decisions

200232

Dear members, As patients and caregivers, we have more sources of medical information available to us than ever before to help us make the best decisions possible for our health. Advice from our doctors is sometimes not the same as the information we learn from the experiences of our peers, and there are often other sources of information available as well. Some of our decisions feel ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

Voice-to-Text Typing and Other Recent Changes

ErikInspire's journal

ErikInspire

voice-to-text-typing-and-other-recent-changes

200232

  • 155 Replies )
  • Processing ...

You’ve probably noticed for the last few days the new little microphone that has appeared on the right side of text boxes when you write a new post or comment. That new feature is called Voice-to-Text. If you click on it, and if you have a microphone, you can speak your text instead of typing it and have it appear on the screen. If you have a phone or tablet, this should happen automatically ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

Post whipple --Is diabetic condition inevitable?

In: Living with PNET

PNET

post-whipple-is-diabetic-condition-inevitable

200232

I had my whipple (for removing head of pancreas for primaries) in september 2013, and presently on sandostatin for liver mets. Tail of pancreas is intact, But the recent blood works suggest that i am moving towards Diabetes and am advised to start on small dose of Cetapin --(Metformin)500mg. Can we assume that all whipple candidates are prone to this and as years progress, is it inevitable ... Read More

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Pancreatic Neuroendocrine Tumor (PNET)

What’s the story of your rare disease diagnosis?

Brian's journal

Brian

whats-the-story-of-your-rare-disease-diagnosis-1

200232

Dear members, Today, more than 200,000 Inspire members have a rare condition. You have made Inspire a place to share your experiences with others who understand what you’re going through and help others at the same time. Many of you have described how long it took for you to receive an accurate diagnosis for your rare condition, while some of you found your diagnosis quickly. If you’d ... Read More

Pancreatic Neuroendocrine Tumor (PNET)

PD-1 blockade resistance

fighterm's journal

fighterm

pd-1-blockade-resistance

200232

Despite compelling antitumour activity of pd-1/pd-l1 blockade, resistance to these therapies has increasingly been observed. It shows that immunotherapy can also select for the subclones insensitive to T-cell mediated attack. There are several mechanisms of the resistance development (after initial great response) recently uncovered. Maybe more in the future. Luckily the resistance ... Read More

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