Why in the World didn’t my oncologist mention Melatonin?

Recently I noticed that in the responses to a post, no one there had addressed the issue of the wife’s problems sleeping. So, remembering how much Melatonin had helped me sleep during and since radiation and remembering that it was supposed to be helpful with the cancer itself, I went to Google Scholar and queried – Melatonin Cancer -- and came up with:

http://scholar.google.com/scholar?hl=en&q=melatonin+cancer&btnG=Search&as_s dt=0%2C21&as_ylo=&as_vis=0

This is not cutting edge science, because there are many postings going back for years that suggest that Melatonin has advantages against cancer, especially non-small cell lung cancer.

Look at this relatively recent one:

http://www.springerlink.com/content/3j88215652332760/

Here is another at http://www.ingentaconnect.com/content/ben/cmc/2010/00000017/00000036/art000 04

See the Abstract:
"It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant pineal secretory product, has oncostatic properties in a wide variety of tumors and, especially, in those identified as being hormone-dependent. The objective of the present article is to offer a global and integrative view of the mechanisms involved in the oncostatic actions of this indoleamine. Due to the wide spectrum of melatonin's actions, the mechanisms that may be involved in its ability to counteract tumor growth are varied. These include: a) antioxidant effects; b) regulation of the estrogen receptor expression and transactivation; c) modulation of the enzymes involved in the local synthesis of estrogens; d) modulation of cell cycle and induction of apoptosis; e) inhibition of telomerase activity; f) inhibition of metastasis; g) prevention of circadian disruption; h) antiangiogenesis; i) epigenetic effects; j) stimulation of cell differentiation; and k) activation of the immune system. The data supporting each of these oncostatic actions of melatonin are summarized in this review. Moreover, the list of actions described may not be exhaustive in terms of how melatonin modulates tumor growth."

I have been taking 15 mg a night, but it looks like 20 are more helpful against cancer.

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