So I'm on Toprol 50 mgs twice a day for months. I went to the cardiologist and told him I'm having a hard time sleeping alot of the time and he asked my dosing schedule. I take them 12 hours apart as recommended, but he tells me I'm taking the last dose too late in the evening. My question is, what happens if I adjust the 12 hour mark? Does anyone else have this problem with toprol or other beta blockers? Thanks in advance for your answers!