Hello, I was diagnosed with Prostate cancer when I was 50. In June of 2005 I was told that I had Cancer and they recommended surgery because I was so young. My Gleason score was 8 but because of the biopsy they believed the cancer was confined to a nodule on the left side of the prostate. I was told that I was very lucky because they believed that the surgery would get it all. After the surgery (August 2005) they told us that it was far more advanced than they thought. But they were optimistic that they had removed all of the cancer. PSA started climbing about 6 months later but at a very slow rate so they did not worry too much. My PSA was 2.8 when they did the surgery and 0.1 after the surgery. When it reached 7.2 in 2007, it was decided that radiation was next. After 35 treatments (every day foir 7 weeks, except weekends) the PSA did not change. After that they did hormone blocking and numerous other drugs and finally chemo in 2011. Chemo did not work so after 6 treatments that was stopped. I am now on Zytiga. I have asked my oncologist what the expectation is from this drug and all he says is that it is very promising. My question is this - Has anyone been on this drug and for how long and has it helped? My PSA which was 296 at the start of the Zytiga, has gone to 118 and now is 165. All in about 10 weeks. Everything I have read does not indicate a whole lot of time left and I am wondering if there is something else I should be doing.