On my 6 mth follow-up, my TSH was 3.95 and they decided they wanted me suppressed. So they doubled my Synthroid from 50mg to 100mg. The endo said she wanted me to come off the T3 (she didn't think I needed it and I was just on the wrong dosage, etc.). So I came home and did just that.... instantly I felt awful. I got so tired I HAD to take a mid afternoon nap and then go to bed by 9 pm. I did this for almost three weeks. I didn't want to have to pay for another med I really didn't need either. Yet, I couldn't understand why I felt worse. If taking 50mg made me tired but functioning... wouldn't 100mg make me feel better, not crazy tired??? Anyway, I just couldn't stand it anymore and took the T3. Again, INSTANTLY I felt better. I have been on T3 now for only 4 days and had enough energy to bike ride 12 miles yesterday and no naps since being on it. Surely this can't be a coincidence? I messaged the doctor and told her I had started T3 again and it just wasn't an option :) Sure she looooved that. Just thought I would share. I'm my own little medical experiment.