I was hoping that I could get some help with a question that has been on my mind for months now. I have been taking methotrexate for 10 months now, ever since I was diagnosed with PsA. I hear that when taking methotrexate we need to avoid people with viruses and I hear that we are at higher risk for infections. I do not quite understand. When you are on methotrexate does it increase your chances of getting sick?? Am I at higher risk of getting sick and if so is it more often? And if so, when you do get sick, say with a virus, do we suffer worse because of our weakened immune systems than if we did not have a weakened immune system? And if we get infections, are they worse than they would be w/o the weakened immune system?? Luckily I haven't been sick once since starting on the mtx. last April, but have recently had my doseage increased from taking 12.5mg to 20mg and fear that with an increased dose of mtx. I am at higher risk for worse side effects. Is that correct? Do our risks for side effects increase with our doseage increases? I would really appreciate some feedback on this subject as I am just clueless.
Thank you all,