I have been ill for many years and was treated incorrectly for Fibromyalgia for many years (about 15). I have had 3 spinal operations. I have constant pain however some days I can tolerate it better than others. Have been on Methotrexate and Arava for over a year. Started loosing hair, have lots of bruises etc. My Dr has applied for Enbrel and I should start at the end of the week. I thought I would come off Methorexate 1st. I had terrible migraines. I have about 20 a month. I then decided to stop the Arava and go back on Methotrexate. My health is definately worse after stopping the meds. Is anyone on Enbrel? What have your side effects been? Has it helped?