I am so annoyed that there is no literature to support doctors nor patients on what happens after you stop prednisone after long term use. The assumptions being made is that we dont understand the importance of tapering - yes you taper but after you stop using such a strong drug after there will be an impact. After 2 years on the zone and 8 months of tapering I am, depletedz, weak, I have a runing tummy I have pins and needles and my body aches all the time, my periods are irregular after 9 weeks of stopping the drug. I have had diabetes, lupus, nerve conduction tests and nothing comes up, my pulmunologist says it is propbably withdrawals - is there any real research or any doctor who is willing to actually give us a clear explanation is too what we can expect after being properly weaned off and for how long ?! HELP!