Moon face, camel hump, bloated belly, acne, increased appetite and other side effects associated with Prednisone. I'm here to tell all how to manage the side effects and reduce weight gain. The key to losing weight while on prednisone is to increase your fruit and vegetable intake and excercise. Stay away or limit sodas and/or fruit juices high in sugar. Stay away from packaged and processed foods because they contain the most sodium. If you can add jumping rope or brisk walking to your routine this will help with the weight gain and other side effects that may occur. Now controlling hunger from artificial hunger! Sounds funny right, LOL!! I know when I;m hungry and I need food for energy and I can tell when I hungry due to the prednisone. Now if you had a nice lunch and find yourself 10-20 mins later hungry again. It could be the medicine. If you have to tame the hunger pang, snack on some nuts or fruits. I usually aim for my trail mix and that gives me a great source of protein which helps me with those steroid induced hunger pangs. If anyone has had success with losing weight while taking steroids; please share! Thanks!