Went through the discussion on vitamin D. Contained much good info and some misinformation.
Vit. D comes primarily from the sun and only a small percentage of people get enough sun in this and many other countries. The labs list 30 to 100 ng. as normal levels (75 to 250 nmol. for those of you outside the U.S.) however in more natural conditions near the equator the levels is closer to 100 ng. than 30 ng. Studies have shown that people with scleroderma and other connective tissue diseases tend to have low levels and the theory, backed by research, is that the very low levels make it easier for the body to produce abnormal antibodies that cause these diseases in people who are prone to it for whatever reason, (won't get into theories on causes of scleroderma). It's already been proven that to help prevent the widespread condition osteoporosis a level over 40 ng.
is important; recent studies give evidence to prevent a large % of breast cancer in women a level of over 47 ng. is needed. 25-hydroxyvit. D levels are easily obtained in a blood test that in the US are covered by insurance in most cases with the proper accurate code. (I've of various problems with getting a level in some other countries). In order to get an overdose, a very very massive dose of vitamin D would be required, a dose that would never be recommended by a physician. If it helps to put this post in perspective, I am a physician who since 2005 has tested 6,000 patients for vit. D levels and treated the over 4500 who are low (below 32 ng). Since scleroderma is fortunately a rare disease and I am not a rheumatologist, I have treated only one person with scleroderma (severe) for vit. D deficiency and have seen quite a dramatic subjective and objective improvement over 2 years. I've searched the medical literature and there are some studies on vit D and the connection to scleroderma, but not much research has been done on this one particular aspect. Best wishes to all who suffer from this terrible illness who read this.