I just went for my regular 3 month check with my rheumatologist and she is wanting me to start a low dose of prednisone (5 mg) due to a continuous problem with swollen joints, much pain (take Tramadol for that), very poor energy etc.. I am on Plaquinel, take several supplements that are supposed to help with inflamation, do yoga and am careful about my diet. I remember a Doctor at a conference (one recommended from this site) who said there is never a reason for a scleroderma patient to take prednisone. I am worried about taking this and also worried about weight gain (I struggle with my weight which certainly doesn't help my joints). I am still able to work, although I have no energy after 1 or 2pm. This interferes with excercising and getting anything done at home. My doctor doesn't feel she can put me on anything that may cause problems with my stomach due to having barretts esophagus and watermelon stomach. I just wanted to see what kind of experience others have had with Prednisone and ideas about this. I appreciate your feedback.