In the fall of 2006, I had a flu shot at the urging of my primary care. I was a pharma rep who was in and out of offices full of sick people. Reluctantly, I agreed. About a week prior to the shot, I also had a back injection for a herniated disc. I was getting those on and off for a few months. I never had a reaction to the back injections but with in hours of getting the flu shot, my chest started to tighten and I felt like I was getting sick. Within two weeks, I had gained 10 pounds, could barely walk..my calves were so tight and painful. My fingers were so swollen. A month after the flu shot, I developed Raynauds. I still felt awful..fatigued and just not my self. Went through a battery of tests..the thought was maybe I was allergic to eggs; negative. My ANA went from normal in 2005 to 1280 in 2006. I have never heard of anyone else with this high of an ANA. I now have nail bed changes in addition to the Raynauds. The titers that tell the specific type of Scleroderma are negative. My pulmonary function tests/EKG are all negative. Yet based on the high ANA, nail bed changes/swelling in my hands and Raynauds, my Rheumatologist is convinced that I have Scleroderma. As to what type, is to be determined. Has anyone else had a similar experience??