After being diagnosed with diffuse systemic scleroderma my Rheum recommended Methotrexate. She said that it would stop the progression of the disease. She said that once I started to experience a symptom from the disease there is no reversing or erasing it, if that makes sense. It only took me two weeks to decide to start the meds. I wanted to stay as normal as I could for as long as I could. I have been taking Methotrexate along with Folic Acid for 10 months now. I am curious about others that take this medication. Has it indeed stopped the progression of your disease? And what is the length of time that you have been taking it? What have you seen as any positives or negatives of the medication?