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Help!! CA 125 numbers and lymphodima??

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Can Lymphodima cause CA 125 numbers to increase? My mom's leg has swollen over the last two month. She has Ovarian for the third time and is on Chemo monthly for good. She just had a CA 125 done in June and it was 1800 which raised from 800, then went in and had a CT which said spots that were on her lung and liver are totally gone and there was a different spot on her other lung that had grown a little. Good news!!! Well then they called her last night to tell her that her CA125 had increased and is 3100! She is very confused and wondering what else can cause the increase. Anyone that can help would be great!!!!

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