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Just curious as to how many women diagnosed with Borderline ovc have undergone chemo vs just surgery.
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Borderline and Chemo
- By Sandiestar
- Posted June 7, 2009 at 7:41 pm · 8 replies
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- By Talismom
- Posted June 7, 2009 at 11:19 pm
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I did just surgery, but it came back in a lymph node 4 years later, they say it is very unusual. I would talk with my dr.
- By felter
- Posted June 8, 2009 at 6:01 am
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It all depends on the cancer type. Mine was Stage 1a (early stage)& surgery normally is enough but I have clear cell which is aggressive & have been recommended - both by onc/gyn & many members of this group- to have chemo as it improves your chances of non recurrence. I have my 1st chemo next week. So you need to know the cell type as well before deciding.
- By moorejmo
- Posted June 8, 2009 at 7:09 am
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I had surgery and It has been recommended by my gyn/onc to have chemo because I to have clear cell. I go on Tuesday to find out all of the details.
- By Mikat
- Posted June 8, 2009 at 10:11 am
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I had 1a as well, but grade 2, so it was recommended that I have chemo and I had 6 rounds of carbo only (had allergic reaction to taxol) finishing last October. If I had been a grade1 I probably wouldn't have had chemo at all. Since I was such an unusual case (they don't usually catch it this early as you know), we weren't sure if we should do the chemo . . would it cause more harm than good? We consulted with several doctors, including a doctor from Northwest who was on the board that made the protocol chart. In the end I felt good about our decision.
- By sbender3
- Posted June 8, 2009 at 11:20 am
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who knows with ovarian cancer-they are now saying that women who are treated before they have symptoms live no longer than those who do not get trated until they have symptoms. so, if that is the case, all that happens is chemo is put in our body, that may not work, and if it was used later may have worked...just like now, using one drug, using lesser dose single treatments, etc, and proplonging lives.
- By Ahavine
- Posted June 8, 2009 at 11:28 am
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My wife was found to have microscopic trace of OC on the surface of one ovary in March after a prophylactic oopherectomy. She was d'xd as a fully-staged 1c after subsequent optimal TAH (in April) showed no further signs of OC.
The Oncologist sought the opinion of the person he considers to be 'the best in the world' to decide on Chemo or not. The conclusion was 'no chemo' because the OC was Grade 2. Had it been Gr 3, chemo would have been recommended.
This is supported by research published in May 2009 'Adjuvant (post-surgery) chemotherapy for early stage ovarian cancer'. This is published in the US Obstetrics & Gynecology Journal Vol 113 Issue 5 and says that women who had optimal surgical staging of their disease 'were unlikely to benefit from adjuvant chemotherapy'...NB 'early stage'.
Search
www.ncbi.nlm.nih.gov/pubmed/19384135
In my wife's case, it seems that the likelihood of the chemo being successful was not worth the risks involved in chemo.
We go back to the Oncology Gyne next week and I expect we will hear more on this topic.
This is surely a tough call and may differ on a case by case basis. Most importantly, my wife is happy with the decision.
- By curiouscat
- Posted June 8, 2009 at 2:09 pm
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It's hard to tell which posters on this thread were truly borderline and which had actual cancer. "Borderline" tumors are classified as the following (regardless of stage):
atypical proliferating serous tumor (APST)
atypical proliferating mucinous tumor (APMT)
atypical proliferating clear cell tumor (APCCT)
atypical proliferating endometroid tumor (APET)
atypical proliferating transitional tumor (APTT)
And then there's micropapillary serous carcinomas which are low-grade malignancies.
According to the Johns Hopkins website, the first 5 generally behave benignly and the MPSC is usually treated with some kind of chemo. Borderline is not the same as cancer that's caught early.
Having said that, I had a TAH/BSO, diagnosed with APST stage 1c. No chemo recommended.
- By carolfitz
- Posted June 8, 2009 at 3:10 pm
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My tumor was classified Borderline LMP Serus lllc
Non-invasive spot on bowel and a few cells, all less than 1cm
Complete debulking, 11 rounds of Carbo/Taxetere until allergic reaction to carbo.
CA 124 never went below 127
Switch to Doxil with rise to 157 after 3 treatments.
There is not much info on this type of cancer other than it does not respond to platinum based chemo.
I can attest to thatt, however it is still considered the "gold standard" for OC treatments.
There is a trial for recurrant borderline underway now. I hope the find something that will work.
Carol
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