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Update on Strontium Citrate Clinical Trial

BoneLady
0 Recommendations

In February, 2009, the University of California at Davis (UCD) announced it would begin recruiting for a clinical trial on strontium citrate for osteoporosis (the SCOPE Study). Since there had been no further updates, I contacted the SCOPE Study Coordinator and asked for the status of the study.

Here is her reply dated May 27, 2009:

At this time, we are recruiting and enrolling participants and will most likely be doing so through the end of the year. No results will be available until at least this time next year.

Explore topics in this discussion:

Jaundice Alli Fractures Osteoporosis Anemia

11 replies

huessysignoret

Bone Lady -- since you are following this, will you post the results for us when they're available? It would be much appreciated.

BoneLady

Hi! huessysignoret,

Yes, I will be following the SCOPE study on strontium citrate (sold as a supplement)and will be happy to post results at NOF.

I am also following the Osteologix clinical trials and patent applications for strontium malonate (to be sold as a prescription drug in U.S. someday when all patents obtained, clinical trials completed, FDA approval gained, and partners with deep pockets found for marketing).

I hope you are well.

BoneLady

zoe311

I've been taking strontium citrate since I broke my arm in December. I read studies wherein the healing time of fractures was reduced, and quality of the mend was improved with this supplement. I bought it from iherb.com. Very inexpensive considering the promise. If you're a new customer code MUR731 will give you $5 off.
I continue to take this, as well as a couple of bone formulas, one by Jarrow and one by Ethical Nutrients.
Both contain a plethora of trace minerals and vitamin K.
I've been frightened into using K having read that without adequate K, the calcium may deposite in unwanted places, such as arterial walls. K's the traffic director, sending calcium where it will do good rather than harm.
If you goto iherb be sure to goto free samples. You can order as many as you like.

BoneLady

Hi! zoe311,

You're the first person I've heard of taking strontium citrate to reduce the healing time of fractures and improve the quality of the mend. But it makes sense to me because strontium promotes bone formation and inhibits bone resorption. Please keep us apprised of your progress.

I visited iherb.com. It has many known brands, including Doctor's Best Strontium Bone Maker, which I take for osteoporosis and buy from another online site. The prices at iherb are very good, with free shipping on orders over $40. Thank you for the tips on getting $5 off for new customers and free samples.

Many people take vitamin K supplements. My multivitamin contains 80 mcg vitamin K, which is also found in green leafy vegetables and many other foods. I don't know how much vitamin K is in your supplement. Just be aware that too much vitamin K can build up and cause red cell breakdown and anemia.

Some people recommend various trace minerals. My multivitamin has several of these. The only ones I am currently taking separately are zinc and selenium.

It sounds like you are taking a proactive stand on your health. Good luck to you.

BoneLady

zoe311

At iherb, if you click the yellow tab LINKS in the top-center of the page, You will find links to: NATURAL LIBRARY; COMMISSION E (German supplement FDA); MEDLINE PLUS; and MEDICAL LIBRARY.
I read some of your old posts and links (from way back) and can tell you enjoy reading.

I'd better read up on K. I never heard about red cell damage. I'm taking Carlson's (cod liver people) K2, 5mg, 1-2X wk. The bottle says daily. It also says 6,250% DV. As used in the Japan studies.

BoneLady

zoe311,

The information about vitamin K and red cell damage is from "Earl Mindell's Vitamin Bible for the 21st Century." The exact quote is: "High doses of vitamin K can build up and cause a red cell breakdown and anemia." The author was talking specifically about synthetic vitamin K (menadione), also called K3, a water-soluble preparation available for adults only per Medline.

The diethealthclub website says "Large doses of vitamin K over a prolonged period can be toxic. In premature infants there can be anemia and jaundice. In adults it may be hemorrhages and kidney disorders." The type of vitamin K was not specified. The link is http://www.diethealthclub.com/daily-menu/vitamin-k.html.

Medlineplus, the most authoritative of the three sources, writes this: "Liver damage has been reported rarely in infants and children with use of the vitamin K preparation Menadiol (not available in the U.S.)....Damage to red blood cells causing anemia (hemolysis) has been reported rarely in infants and children with the use of the vitamin K preparation Menadiol...."

I see that you are taking K2, the type made by bacteria in the human gut. Most references I found were for K1, found naturally in plants and manufactured for medicinal use under several brand names, or for K3 (menadione).

I checked out the yellow tab "LINKS" at iherb, as you suggested. The site is a wonderful resource. I will have to keep it in mind.

BoneLady

Alli

Hi bonelady which multi vitamin are u taking that has 80 mcg's in it.... i am taking vit k mk7 separately but i am always looking at new ways....

BoneLady

Hi! Alli, My current multivitamin is Nature Made Multi For Him. Sometimes I buy Nature Made Multi For Her. The two formulas are very similar, so I just get one or the other, whichever is available, so that my husband and I can take the same multi. We buy it when it is on sale for buy one, get one free. I also clip coupons from the newspaper. We buy it at Walgreen's, but CVS and several food stores and stores like K-Mart also carry this brand.

It contains no iron and is a complete multi vitamin/multi mineral formula.

Becka

Here is a link to some more information about Bones and Strontium. A few steps are involved to get to the actual article.

(1) www.tahoma-clinic.com/articles.shtml

(2) Look for the article: Fight - even prevent - osteoporosis with the hidden secrets of this bone-building miracle mineral
STRONTIUM....

(3) THEN SCROLL DOWN TO: A bone-building timeline.

Very interesting.

BoneLady

Becka, I had read this article some months ago and it is very interesting. Apparently, Servier, the French company that makes strontium ranelate objected to Dr. Wright's article promoting AOR Strontium Support (strontium citrate) while citing studies on strontium ranelate carried out by Servier.

To read Dr. Wright's original article and the letter from Servier's lawyers, follow Becka's links. Below is Dr. Wright's revised statement following Servier's objections:

"As to natural strontium: Mayo Clinic researchers noted clinical and x-ray improvement in severe osteoporosis with strontium lactate (footnote 4 to the Article below); Dr. Marie reported significant microscopic improvement in bone with the use of strontium carbonate (footnote 6 to the Article below); Dr. Jonathan Wright has observed significant improvement in bone-density with the use of strontium citrate. These observations about natural strontium, however, are not precisely the same as those made about the semi-synthetic compound, strontium ranelate, which has been the subject of placebo-controlled, double-blind studies differing from the studies of others. Each piece of research should be judged on its own merits. Despite distinctions among these studies, Dr. Wright's conclusion about strontium compounds remains the same: strontium compounds are highly efficacious in preventing and combating osteoporosis."

BoneLady

Alli

thanks bonelady will check it out

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