Lupron and osteoporosis

• By centersheila
• Reply 3337547 · In reply to 3319629 by dxaguru
• August 31, 2012 at 7:28 pm
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First of all, the reason the osteoperosis was diagnosed was because I had five fractured ribs, which I do not know I got. In your message you said "At least it was discovered before you had any broken bones" (or something to that effect The cat scan showed two fairly new rib fractures and three brand new ones. THe pain was incredible. I have been on disability for two months.

I not only have osteroperosis, I also have SEVERE bone thinning. It is not my fault that my doctor did not inform me that I should have a bone scan prior to Lupron treatment, and it was only because of the 5 rib fractures that I received a bone densisty scan at all. And not to be rude, but yes, I can blame it on the lupron. I can also blame my fatty liver that has a lesion on it on Lupron. My doctor told me that this is consistant with hormone thereapy. AT 52 years old I would suspect that I would have indications of my bones getting older, but please. . . . . like that of a 80 year old, really. I mean no offense to you, I know you words were meant to comfort and that your intentions were good. But the fact that you told me I can't blame it on the Lupron when I know that is what caused it has really rubbed me the wrong way. With all due respect.

• By sewdusty
• Reply 3338843
• September 1, 2012 at 10:28 am
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centersheila, I am sorry that this has happened to you. We are here to help support you.

• By shersita
• Reply 3446255
• October 10, 2012 at 7:48 am
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Hello.

I'm very sorry about what Lupron Depot did to you. I used Lupron Depot for 10 months because of big fibroids on my womb, and it did reduce them like 70% of their size so surgery was very fast without any further problem on my womb. The doctor seemed worried when I told him I used Lupron for 10 months straight and did prescribe to me a bone density test which I never had, so maybe I do have osteoporosis too and still don't know it. I'm 31 years old, and I also have fatty liver (not because of Lupron, maybe because I eat too much fatty food even if I wasn't overweight at all when diagnosed). I read later on that Lupron should not be taken if the person has liver disease...unfortunately, I found out this after 2 Lupron shots of 3 month each, the good news is that apparentely Lupron didn't affect my fatty liver since blood test of liver enzymes were normal, so my liver wasn't inflamed and that's a good sign on fatty liver.

My surgery was last year and I stopped Lupron after it, it has been a year and a half now I still have the fatty liver, don't know if it is inflamed or not, since I need blood test to find out. I don't know anything about my bones density though, I feel that maybe Lupron did reduce my bone density, but I still haven't have any broken bones (I think or haven't been aware of) and I practice martial arts and this is risky with fragile bones..

I just hope, you get better and maybe find some treatment to make bones a little more harder.

• By Thomaseena
• Reply 3500376
• October 29, 2012 at 9:48 pm
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I felt like I was losing my mind when I was taking Lupron. I didn't take it very long, but was changed to Depo Provera shots for endometriosis. After years of that, a hysterectomy at ag 39 (and Nexium) I've got osteoporosis as well.

• By centersheila
• Reply 3503460
• October 31, 2012 at 12:53 am
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I don't know how long you were on lupron. I was on it 15 months,51 when I started and 52 when I stopped. Some time after I started the injections I was told I had a fatty liver, another doctor told me I had a lesion on my liver which she felt was consistent with hormone therapy. I healed from my 5 unexplained fractured ribs, and now, after having had osteoarthitis in my right hip, need a hip replacement as the doctor said it is bone on bone. I have severe enough bone thining and osteoporosis that now they want me to see an endocronolgist. I was premenopausal when I received treatment and in my heart, I know this drug was just too much for my bones and that is the root of my problems. Time will tell, or it won't. I was too young for osteoporosis, have no family history of it, didn't do things to my body that would cause it etc. My doctor tells me he has only performed 2 hip replacements on patients my age or younger. That is because it is uncommon. I don't think anyone knows exactly what damage this drug does, and maybe never will. I hope the best for anyone who has suffered from this drug. God bless.

• By lkw787
• Reply 3503491
• October 31, 2012 at 1:22 am
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I don't know if lupron contributed to MY osteoporosis. I did only one lupron cycle but many cycles of stimulated IUI and attempts at IVF before moving on to DE IVF at age 44. Now at 46 I find myself with increasing joint pain and stiffness and have been diagnosed with osteoporosis/osteopenia and have been told to increase my intake of D3, calcium and weight bearing exercise.

I can't help but think that all the years of fertility treatments sped up the age at which I went into menopause and somehow contributed to my osteoporisis/osteopenia.

I was also put on keppra (an antiseizure medicine) for two and a half years after coming down with HELLP Syndrome when my DD was born and I'm wondering if keppra increased the odds of getting osteoporosis or contributed to joint pain.

Good luck to you!

Sincerely,

Lisa