forteo and osteosarcoma

My mother was a fairly healthy woman, she was 73 years old, she had arthritis, osteoporosis and gerd. No heart problems, no high blood pressure she was pretty healthy. We were introduced to forteo summer of 2007 because when she took the fosamax or boniva it would upset her stomach. We were told by her Dr. there is a new drug on the market, its a 2year process to help build new bone and she is a perfect candidate. She was real excited. She started it 2007 I would give her the shot of forteo in her tummy every night. As far as she could tell no side affects at that time. Bone density results came back with a very little change for the better so she continued. After a little over a year or right at 1 year she was complaining of her stomach always sore and cramping and then vomiting. A sore appeared on the top of her head that would not go away and getting bigger approx the size a quarter, we went to the Dr and they sent us to a specialist or dermatologist that said it was a basal cell carcinoma (skin cancer) they lanced it or dug it out basically it looked to be approx 1/4 in deep they went and they said it was all gone. a couple of weeks or so after she had a cough that would not go away, we took her to her dr and he did a chest ray checking on her lungs, he saw a dark area and referred us to a pulmonologist, he did a scan and before he would confirm anything he sent her for a pet scan. results she has numerous nodules. 1 in left lung, 1 in stomach wall, 1 right hip and another on spine. they also did a biopsy on the one in stomach. final results were given over the phone to my sister. our mother who was healthy a year and half is now at stage 4 osteosarcoma and surgery is not an option. We got in touch with a Oncologist and she decided to try chemo (because my sister and I wanted her to try) that was horrible, then radiation on spine and hip after a few sessions she could barely walk. We lost our precious mother 12/09 she was diagnosed with osteosarcoma 2/09 already at stage 4

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I am so sorry you had to lose your mom under the worst possible circumstances. She was fortunate to have two daughters who were with her every step of the way. I took care of my mom the year before she died, it is not an easy walk, but an honorable one. God bless, Marilyn

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Marilyn you are so right :) thank you. Aloha Tracie

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Tracier;
I am so sorry for the loss of your mother.
please know that you are not alone.

A dear friend of mine on here lost her dad to the bisphosphonates also.
Please look her up at http://www.inspire.com/acook4/
She is a wonderful soul also.
Lost, like the rest of us with all this disinformation about the drugs.

Much like cancer, there are no miracle cures.
Nothing that time, exercise and diet won't help anyway.

Best to you.
Peace.
"P"

Also another man who writes of losing his wife.
http://www.inspire.com/groups/national-osteoporosis-foundation/discussion/d eath-by-reclast-janets-story-1/?ref=as&asat=1318249

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I am on Forteo, my 4 th month now. When I told
My daughter that it caused osteosarcoma in rats ,
She asked me not to take it.
Your story is making me rethink this.
I am so sorry for your loss.

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I am sure you know my response and that of course is please dont take it listen to your daughter. Eventually I hope Forteo will no longer be prescribed. Until then some people will benefit and some will no longer be here to explain their story. Reading all these different articles on Forteo including the FDA there have been reported deaths from Forteo but they do not have a number or percentage on how many.

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hehehe
I posted my 'reply' on the wrong discussion!
No matter- everyone needs the info anyway.

Just going to copy/paste it here...
"P"
-------------------------------------------------------
About FORTEO

From here:
http://www.betterbones.com/osteoporosis/forteo-bonedrug.aspx

Rethinking osteoporosis MORE, BELOW

Forteo — is this bone drug too good to be true?

As the manufacturer reports, the longest studies on the safety and efficacy of Forteo were of only a two-year duration. Why are there only short-term studies on this new drug? There are only short-term studies because in the animal safety studies, Forteo was shown to cause a high incidence of osteosarcoma (a rare malignant, often fatal, bone tumor), as well as osteoblastoma (abnormal mass of tissue in bone) and osteoma (small benign bone lesions). As with all drug safety tests, the drug doses tested were from 3-, 20-, and at times, 60-fold higher than those used in human medications. Notably, bone tumors were observed at all Forteo doses, with the incidence reaching 40–50% in the higher-dose groups.

Given this major safety concern, human trials with this drug were terminated early and guidelines were set to limit the duration of its use in humans. In fact, as the manufacturer specifically states, “The safety and efficacy of Forteo have not been evaluated beyond two years (median 19 months in women and 10 months in men). Consequently, the maximum lifetime exposure to Forteo for an individual patient is 18 months.” Also, given the cancer-causing effect of the drug, the FDA required a “black box” label warning, clearly stating the increased cancer risk shown in rat studies.
Expensive, experimental, possibly cancer-causing, and inconvenient
As near as I can calculate, since its development, studies on this drug have included only 1943 patients. According to the manufacturer, a study of one year is considered “long term,” while the maximum length of any study was only two years. Thus, not only is Forteo relatively new, but it is also experimental and, I would say, inadequately tested. In addition, it is very expensive — the drug costs upwards of $600–$700 per month! Further, it is inconvenient to use as it must be given as a daily self-administered injection. Most importantly, since this drug has shown to cause cancer in rat safety studies, its use by humans is limited to two years or less. While there may be significant bone density gains while using Forteo, the research is clear that these gains are lost once the drug is stopped. To maintain bone density gains, antiresorptive drugs such as Fosamax must be used after stopping Forteo.

Is there a better way?
This is the question I constantly ask myself — is there a better way to increase bone strength and reduce needless osteoporotic fractures? Is there a way that does not run the risk of causing cancer, or lead to excessive new bone formation — a way that is not only safe, but also good for the entire body? Yes, in most cases there is another way, and that way is through a comprehensive, life-supporting bone-building program that enlivens natural human healing and the body’s regenerative capacity.

To learn more on the topic of osteoporosis and bone loss, read the additional articles on the click above-
Last Modified: 06/24/2009
Principal Author: Dr. Susan E. Brown, PhD
----------------------------------------------------------

There is LOTS more info if you click on the link, and go from there!

Best.
"P"

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Now for the lowdown on the poisonous bisphosphonates...
Which include the following:

Name Brand --- Generic equivalent:
**Actonel --- risedronate
**Boniva --- ibandronate
**Fosamax --- alendronate
**Fosamax Plus D --- also alendronate
**Skelid --- tiludronate
**Didronel --- etidronate
**Aredia --- pamidronate
**Zometa --- zolendronic acid
**Bonefos --- clodronate
**Reclast --- also zolendronic acid
(To name the most widely prescribed).


Please read this;
https://www.inspire.com/PSput/journal/osteopenia-porosis-foods-diet-exercis e-and-magic-drugs/

Know that they LIED about osteopenia JUST TO SCARE PEOPLE and make money!!!
(And if they lied about that, you can only imagine how much lying has gone on about our osteoporosis too).

Best.
"P"

Also please read this-
Know that this is only ONE (of too many) horror stories about bisphosphonates; (& DARKLY POISONOUS 'medications') -if you can call them that.

http://www.inspire.com/groups/national-osteoporosis-foundation/discussion/d eath-by-reclast-janets-story-1/?ref=as&asat=1318249

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@Tracier so sorry to hear about your mother, my condolences to you & your family!

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I am so sorry you lost your Mom. Osteosarcoma, is a big risk as I see it. Given the research, this is a very dangerous drug. How can the drug companies continue to harm patients. Please inform the FDA of her death due to this drug

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Tracier
I am really sorry for your loss. That must have been a terrible ordeal for you and your family. My father died of bone cancer so I know how awful it was. I'm glad you did this post because if there are other cases out there we will hopefully hear about them. Like many people on this site I felt I had little choice but to take one of these drugs as I was fracturing every two weeks. The pain and subsequent disability is awful. I have now gone five months fracture free on Forteo. In one of Psput's earlier links (the microchip discussion) it said
"So far, only one case of osteosarcoma has been reported among the 250,000 patients for whom Forteo reportedly has been prescribed since it was introduced in 2002. The patient was a woman, postmenopausal, in her second year of treatment and had other serious medical problems in addition to her osteoporosis. She has since died." Are there many others? I would really like to know what the risk factors for developing osteosarcoma really are.

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Tracier,

I am so very sorry for your loss. I wish I could say that I have no idea what you are going through, but I lost my father to an Osteo drug too. He died just 54 days after taking Reclast. We were very close, and like you, I was with him through this whole ordeal... every step of the way from the second he received this infusion, to the second that he took his last breath. I have run the gamut of emotions, and I still feel the pain of his loss everyday. I can't let him go entirely as long as these drugs are out there destroying other lives, and leaving families wondering what just happened??

I have not researched Forteo much, but know of the dangers associated with this drug, and I must say it makes me wary. Why don't we all reason that going the natural route to bone health should ALWAYS be our first line of defense. Drs. are so busy scaring us silly, and push,push, pushing these powerful, poisonous drugs on us. What other reason is there than ignorance or money... if there is another reason I can't see it.

I am sure that you have learned many lessons from this experience with your mom...hard lessons. My heart goes out to you, I feel your pain.

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DrugVictim,

If you do decide to discontinue the Forteo, you may want to consider taking LactoFerrin. It is a milk/whey based supplement that has been found to actually grow bone, and without any side effects. I've been taking it for a few weeks along with K2-Mk4, DHEA, and now Boron. Good luck to you.

Tom

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Drugvictim--You brought this discussion to my attention. You didn't ask for my opinion, but I'll give it anyway. I would stop treatment. Studies have shown that micronutrients, like the ones that I am taking are just as successful as bisphosphonates, without all the side effects.

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Just terrible. I am so sorry for your loss. 73 is way too young to die. Especially with someone in such good health.

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I have to say I really did not think I would have any responses. I stummbled on this website and felt I needed to share what has been built up in me since 2009. It's such a sad situation. Here we are giving our full trust to Dr's, Pharmacist and drug companies to get healthy, have a longer life and yet we are guinea pigs, experiements to help them make more money is what is all boils down too. The other thing I did not mention in regards to my Mom is our Doctor is family he is my nephews father in law. My mothers 1st grandson's father in law and he never did mention the "black box warning" side effects, he did say to my mom you are healthy and would live to be in the middle 80's or longer. It's hard to look at him at Christmas, Easter, other family get togethers. Of course he did not intentionally prescribe our mom her death sentence but he is one of the ones that is in it for the money. Making the drug companies money not even knowing he is taking away our loved ones.

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