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This has been around for a few years. I just came across the info. It sure sounds interesting! Jill
http://femarelle.com/content/view/21/57/
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Anyone heard of Femarelle?
- By JilleWhite
- Posted May 23, 2009 at 7:30 pm · 11 replies
- In Vitamins and supplements
- Shared with the public
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- By catwoman
- Posted May 24, 2009 at 8:22 am
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I had never heard of it, but went to the site you posted. It sounded intersting, but when I learned it was a SERM I went to collected information I have on other SERMS (Evista and Fablyn)- which both seem to have increased risk of blood clots- not something to be taken lightly (especially for me with a personal and family history!) You'd have to weigh the risks for yourself.
- By Char42
- Posted May 24, 2009 at 10:27 am
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Femarelle is still being tested on the coagulation system, therefore might not be the best choice for those with a history of blood clots. I am on Coumadin for a genetic blood clot disorder. For those women that do not fall in that category this might be helpful.
http://clinicaltrials.gov/ct2/show/NCT00883272
- By Jo-Ann
- Posted June 10, 2009 at 8:43 pm
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Does anybody know it this product is available in Canada?
- By rmchavin
- Posted June 12, 2009 at 10:44 am
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Dear JilleWhite:
I can't understand why you would be so unimpressed by a well-researched, well-understood, widely prescribed, highly praised SERM like Evista (raloxifene), which has been used by postmenopausal women since 1998, but be so interested in a risky, new, poorly researched SERM like Femarelle (DT56a). Here's are 3 PubMed research studies on Femarelle: http://www.ncbi.nlm.nih.gov/pubmed/17428655 http://www.ncbi.nlm.nih.gov/pubmed/15266766 http://www.ncbi.nlm.nih.gov/pubmed/14627860 As a practical matter, I doubt that you could find a medical doctor who would be willing to prescribe DT56a to you even if you begged him persuasively.
- By rmchavin
- Posted June 13, 2009 at 8:45 am
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Dear JilleWhite:
Have you considered lasofoxifene, basedoxifene, and arzoxifene: http://www.ncbi.nlm.nih.gov/pubmed/19249985
- By rmchavin
- Posted June 13, 2009 at 9:37 am
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You might also want to consider toremifene, droloxifene, idoxifene, levormeloxifene, LY353381, and CP336156: http://www.ncbi.nlm.nih.gov/pubmed/10353293 Of course, you could also consider ospemifene, acolbifene/EM-800, and HMR 3339: http://www.ncbi.nlm.nih.gov/pubmed/16451093 But after all is said and done, you might want to fall back on good, old raloxifene: http://www.ncbi.nlm.nih.gov/pubmed/17503894
- By rmchavin
- Posted June 13, 2009 at 10:23 am
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There was a showdown between the defending champion, raloxifene, and the challenger, bazodoxifene. I'll let everybody judge for themselves as to who won this showdown: http://www.ncbi.nlm.nih.gov/pubmed/18457472 (Hint: I suspect bazodoxifene increased bone density better than raloxifene but raloxifene was superior to bazodoxifene in its effect on various cancers).
- By rmchavin
- Posted June 13, 2009 at 11:09 am
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Whoops. Pardon me for misspelling "bazedoxifene." I incorrectly referred to it earlier as "basedoxifene" and later as "bazodoxifene." However, I'm confident that I spelled everything else correctly.
- By linnyd531
- Posted July 6, 2009 at 9:51 pm
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One does not need a prescription to obtain femarelle. It is a soy based SERM that i believe is different from raloxifene in that it apparently does not target estrogen receptors in the breast or uterine tissue. That of course would be a concern for those of us who may be at an increased risk of breast or uterine cancer. The website for femarelle does have studies backing this info as well as studies showing a significant improvement in bone density. I had submitted a question to the website requesting how specifically this product avoids receptors in the breast and uterus but have not received an answer as of yet.
- By menolady
- Posted August 4, 2009 at 10:21 am
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Dear JilleWhite and others:
I actually have been using Femarelle for the past 6 months and am very pleased with the results so far. I was suffering from severe hot flashes and was waking up a lot during the night. I didn't want to take hormones so my gynecologist suggested I try Femarelle. She has had other patients who had relief after taking it. My overall quality of life has significantly improved! Also, I read somewhere that they completed a study at NYU on clotting and the results were very promising. If I can find the article, I will post the link here later.
- By JilleWhite
- Posted August 6, 2009 at 11:56 am
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Thank you menolady for letting me/us know your results!! I need to look into this again!
Jill
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