Seeking a Research Study to Sponsor

• By Munker
• Posted October 26, 2009 at 7:45 pm
• Report post

I am a participant in a study by Sloane Kettering in NYC but I think the study has been transferred elsewhere. If you contact sloane I am certain they can guide you in the right direction.

• Reply

• By MTaylor70
• Posted October 26, 2009 at 7:54 pm
• Report post

Thanks for your prompt reply Munker! I appreciate the referral. I'll contact Sloane Kettering to find out what studies are underway.

• Reply

• By Munker
• Posted October 26, 2009 at 8:15 pm
• Report post

Good luck and thanks for your efforts. It seems like everyday I hear about another woman who never smoked that is diagnosed with this terrible disease! Not sure what is going on but Iit sure is scary. There may be a connection with estrogen but nothing conclusive. We need lots of money to fund more research!

• Reply

• By tyler2
• Posted October 26, 2009 at 8:21 pm
• Report post

If you don't find a study that focuses exclusively on non-smokers, you could sponsor one that deals with inhibiting specific mutations in the EGFR (Epidermal Groth Factor Receptor). This mutation is most commonly found in female non-smokers (and is more common in Asians that other races).

The exciting news is that Targeted therapies (pills that attack the specific cancerous areas) have been successfully developed to stabilize or even reduce lung cancer in most people with these mutations. However eventually the cancer seems to learn to "detour" around the "roadblocks" created by these pills. New research is underway (including clinical trials) to try to understand why the pills often lose their effectiveness over time. The results of these clinical trials, and the information learned about cancer mechanisms, could be expected to have major consequencies for the way lung cancers are treated in the future.

I'm in the process of trying to get some up-to-date information about these new trials and will be happy to pass the information on to you. If you're interested, just send me a "friend" request and I'll be happy to reply as I learn more.

Tyler

• Reply

• By linnea
• Posted October 27, 2009 at 7:43 am
• Report post

MIchelle--that's great that you are raising funds for this cause, your mother would be so proud. And those of us who have the same disease but also never smoked are so grateful for your efforts. Tyler, I have been enrolled in the PF-02341066 trial for over a year now--it targets the ALK mutation which also seems to be found primarily in never smokers. I have had a tremendous response to the trial drug (tarceva did nothing for me) and am knocking on wood that it continues to be effective for some time. Linnea

• Reply

• By keepongoing
• Posted October 27, 2009 at 8:19 am
• Report post

Munker,
Which study at Sloan Kettering are you in? My husband has just been enrolled in a study at Sloan for non smokers with the EGFR mutation which will use Tarceva plus an additional drug identified only as AT-101. I was wondering if this is the one you are in and what you can tell us about the AT 101 drug. What to expect in terms of side effects, etc.
Thanks,
Nili

• Reply

• By Munker
• Posted October 27, 2009 at 9:56 am
• Report post

It's a non smoker study to determine if there is some type of genetic reason for non-smokers who get lc. I was stage one and did not require further treatment. I just had to provide a history, blood samples and saliva samples for the study. Let me look through my records and I will post details.

• Reply

• By ReginaVidaver
• Posted October 28, 2009 at 10:44 am
• Report post

Hi there,

The National Lung Cancer Partnership funds peer-reviewed, competitive research in all facets of lung cancer. Please feel free to contact us at 608-233-7905.

Best,
Regina Vidaver, Ph.D.
Executive Director
National Lung Cancer Partnership

• Reply

Add to the discussion