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ASA404 novartis

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Everyone has been so kind. It really makes you see the good in people!
Is anyone familiar with this drug from novartis ASA404? it is a clinical trial that the oncologist says my father will be a part of, we hope! After receiving the trial information from the oncologist, i tried to understand what it is? i researched it, but really dont understand if it will be layered into his existing chemo which weve been told is no longer working, or is this a single type of drug?
A few weeks ago, i remember reading a few posts in which people were talking about a facility in california, im not sure if it was for conventional treatment or not, but if i remember correctly people were raving about it?
My third question if anyone knows is, do all research studies for cancer have to be approved through the fda? I guess i want to know if all cancer treatment is "mainstream"? are there trials at universities and research facilities that oncologists would not be aware of because it isnot backed by the lge drug companies? thank you for your help.
tom

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Hi Tom
ASA404 is a new and very interesting compound, which Novartis has licensed from another and much smaller company. Probably because they see a big potential for the drug.
The drug works by cutting off blood supply to the tumour, and this will eventually cause the tumour to die. I belive you should try to get your father involved in a trial with the drug if possible - but consult the oncologist. The drug would be useable as single treatment, that is without chemo at the same time.
Trials always should be approved by FDA and by ethical comitees, who overlook that the patients are well informed and selection is ethically correct.
Hope this answer some of your questions. Good luck with the treatment.
Sincerely
Knud

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