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nsaids and probiotics

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I read recently that there have been some studies that suggest regular use of NSAIDS (especially aspirin) and Lactobacillus casei have helped in preventing the recurrence of bladder cancer. Has anyone here tried these and if so what doses etc. My doctor did not recommend this but I figure it can't really hurt? Thoughts?

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Cancer Probiotics Aspirin Bladder cancer

7 replies

Hi and welcome to the community.
NSAIDS taken for extended periods can in "some" people cause other issues, like liver damage or kidney problems. I do know with me I can no longer take NSAIDS because they were irritating the esophagus. and also causing reflux. The probiotics I'm no to sure but I take them because my wife talked me into it.
Keith

Here is a website you might want to look at:

http://www.thecancerblog.com/category/bladder-cancer/

These are short recaps of articles. There is more than one item of interest here. If you want to know more, click on "read" below the recap and you will get the full article. The very first entry mentions nsaids, but not probiotics.

If you are not sensitive to aspirin, I would not think that a daily 81 mg aspirin would harm. Unfortunately, they did not prevent my bc (I have taken daily aspirin for over 20 years), but I have not had cardiovascular problems. Most of the cardiologists I know have taken aspirin for 30 or more years since the early results came in. Other NSAIDS are more of a liver toxicity problem because the effective dosage is closer to the dosage that causes toxicity. Aspirin usage has also been demonstrated to lower risk of colo-rectal carcinoma. I wouldn't think probiotics would hurt. I agree that checking with your urologist and primary care doc is a good idea before changing. Also keep in mind that with aspirin usage clotting will be impaired (usually inconsequentially at an 81 mg/day dosage), but you will need to stop substantially before any surgical procedures.

JJ

I realize that taking NSAIDS (and any drug for that matter) in certain doses can result in deleterious effects on the liver. I was mostly wondering if this was a protocol that anyone has actually been prescribed. It sounds like at this point alot of the results are anecdotal but I wasn't sure if any one out there had any experience with it. Thanks for the info.

I started the aspirin regimen on my own years ago after seeing numerous reports of the cardiovascular advantages. As new information became available about dosage, I dropped the dose to 81 mg. My primary care doc and any other doc that treats me is well aware of this and all prescription and non prescription drugs that I take. I don't know of any protocol for cancers and NSAIDs, however I think the evidence for aspirin came either from patients on the daily 81 mg dose or ones who take aspirin daily for some other reason. I do not know if there have been double blind controlled studies of this or of the combination of probiotics and asa (aspirin).

JJ

I believe that we need to start eating healthier and that our bodies can best make use of the vitamins that we get through nutritious foods.
Kefir is a wonderful drinking yogurt with tons of probiotics.
I believe that many of us needs to really start to take care of our bodies a little better and be a bit more kind to them.(me too I as I have been chronically dehydrated)
It isn't very loving to feed ones body with Kentucky fried chicken but its kind to give it some fresh spinach, broccoli and brussel sprouts.

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Related links from BCAN

Researchers are looking for bladder cancer survivors to complete a telephone survey. Click here for more information.

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Information for those newly diagnosed with bladder cancer from BCAN.

Bladder Cancer Basics for the Newly Diagnosed
Download or order a copy of BCAN's patient handbook "Bladder Cancer Basics for the Newly Diagnosed" free of charge.

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Information about women and bladder cancer from BCAN.

BCAN's glossary (PDF)

BCAN's November Patient Forum in San Francisco
"Understanding Bladder Cancer: A BCAN Patient Forum"
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Saturday, November 7, 2009
9:30 am - 2:30 pm
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Presentations from BCAN's May 2009 Patient Forum
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