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Can anyone explain what this term means

Girly1
0 Recommendations

Yesterday I asked for a copy of my Pathology report from docs office. It says diagnosis is High grade in-situ papillary Urothelial Carcinoma (4 CM in aggregate).I know I had this 1 big tumor and 12 what the doctor called satellite tumors. It also says Muscularis Propria present,what does that mean?For all of you that have been going through this alot longer what does all this mean, Is this really bad? I just had my 6th bcg/interferon yesterday.I just want to hear others opinions about this.

Joan

16 replies

EG-NJMason

Hi Joan. take a look at this.. it may help. Simpler English for what you are reading;

http://apps.pathology.jhu.edu/blogs/bladder/?tag=muscularis-propria

Girly1

Thanks for your reply that article does explain things better for me.

Thanks
Joan

jj803

Hi Joan,

Papillary urothelial carcinoma means that the tumor has a specific growth pattern (papillary) meaning that it is an outward directed growth with many leaf-like projections, somewhat like cauliflower. Urothelial means that the cellular composition is the type of cell that lines the bladder. High grade indicates that the cells have microscopic features substantially different from normal cells and carcinoma in-situ indicates that the tumor has not invaded or spread outside the innermost lining of the bladder. The first level outside of that lining is called the lamina propria and would be the first area invaded when a tumor breaks free of it site of origination in the surface layer. Muscularis propria is also known as the detrussor muscle or the muscular wall of the bladder. Saying that it is present without saying the tumor is in it means that the tumor cannot be demonstrated in the muscle wall in this resection specimen and that the muscle is there to evaluate. Since muscularis propria invasion carries significant prognostic and treatment implications, often it will be stated that muscularis propria is either present or absent. Another good site for interpretation of pathology reports is at mybiopsy.org (http://www.cap.org/apps/docs/reference/myBiopsy/BladderUrothelial.html) the link here is to urothelial carcinoma of the bladder, specifically. Hope this helps some.

JJ

Girly1

Wow what can I say I am impressed. I didnt even get that kind of info from the doctor. Thanks JJ.

Joan

LadyJane123

:-)
Girly
We are so lucky to have JJ as he is a pathologist. Isn't that wonderful? I have learned so much from him. We are certainly blessed to have him here.

nancynursez637

Joan, JJ is our lovable pathologist, who helps us all figure it out!!! /We are so lucky to have him

nancynursez637

We are so lucky to have you among our resources. You do so much for us and we really appreciate it!!

NancyN

jj803

I greatly appreciate your kind remarks. The translation is usually not too hard, knowing what to do is the hard part. Ya'll generally help us all out on those issues. Thanks again

jj

YvonneM

Your awesome JJ.
Yvonne

Moonerj

He sure is Yvonne.
Jack

Ken-E

JJ, You are a cornerstone of this site, great post.....Ken

EG-NJMason

clearly, I won't even attempt to answer questions like that any more !

Bob_M

JJ,

Wow, that was great! Like Joan said, your explanation was more thorough than anything I got at MDA. Then again, maybe it's easier to pay attention "after" being treated. I would never have the patience to learn all those syllables. We ARE lucky to have you!

Take care,
Bob

silgal

JJ - there have been many times you have given answers to others, that have helped me! thank you!
EGMason - the site you gave was helpful too! each time someone replies, it gives hope,.... don't feel you shouldn't answer, every person's contribution is valuable!
Girly, lots of luck with the next step! we're here for you

jj803

EG and all,

EG your response was indeed helpful as it provided a source of information on many things, not to mention it was a response from the head and from the heart, we can ask for nothing more.

And yes, it absolutely makes a difference to have been in the patient role, too. I also think that a pathologist can provide more insight into what the words in a path report mean a little better than a surgeon, oncologist, or internist. Its the language we use all day every day and for the most part we carefully choose each word for its meaning. On the other hand the doc doing the treating is more likely to extract those pieces of information that is important for him to gain prognostic information and determine appropriate treatment alternatives and gloss over the rest. As the patient you want to know what each and every word conveys. Best wishes to you all.

JJ

Girly1

I want to say thank you again to JJ and also EG for your replys, like JJ said every contribution helps. This site is an absolute blessing. I haved learned so much and everyone that has replied has helped me in some way or another, whether it is learning about medical terms, everyones different effects from the same treatments, or an inspirational comment I do appreciate everyone.
Thanks Again
Joan

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