Yesterday I asked a question about end stage GBM and dexamethasone possibly prolonging life. Today I am asking if the end can happen really rapidly. Yesterday he slept most of the day, but was able to take his meds and ate some food. Today he seems much worse. He doesn't want to eat or drink. I had a hard time getting his meds down him both this morn and this evening. I had to force them into his mouth and use a syringe and literally squirt water into his mouth and make him swallow. I am terrified this is the beginning of the end. Can it happen this quickly?