My friend had a lumpectomy for Grade 3 breast cancer on June 30. She started chemo on August 9 and receives subsequent chemo treatments of TC every 3 weeks. She will have 6 cycles in all. She received a shot of Neulasta the day after the last 2 chemo treatments. She is in terrible pain where she literally can't get up off the floor. She doesn't feel like eating, drinking, watching TV, etc. OTCs have no effect. Have any of you found a better way to manage the painful side effects of the this drug? It's great in that it prevents infection while your WBC is so low, but I have to start wondering about risk vs pain.