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Minimal change disease support groups
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Minimal change disease
Minimal change disease is a kidney disorder. Each kidney is made of more than a million units called nephrons. Each nephron has a tuft of blood vessels called a glomerulus, which is surrounded by a structure called the Bowman's Capsule. Together, these structures filter blood and produce urine.
Minimal change disease is one cause of nephrotic syndrome. It is named "minimal change" because the nephrons appear totally normal under a light (regular) microscope. The condition is only seen using an electron microscope, which reveals changes in the glomeruli. Urine tests also show high protein levels. Minimal change disease is the most common cause of nephrotic syndrome in children. It is also frequently seen in adults.