Calcium Orotate

I have taken Calcium Orotate, mostly last year, now not as much because of side effects.

Calcium Orotate—The Best From of Calcium Available
According to studies conducted by Dr. Hans Nieper (Germany) only Calcium Orotate penetrates directly through the cell membrane, delivering calcium to the interior of the cell where it is readily utilized.
Orotates are mineral salts of orotic acid — used by plants and animals to make DNA and RNA. Hans Nieper, a physician and dabbler in offbeat theories of gravitation, used orotates clinically prior to 1980. He thought that orotate salts, being neutrally charged, pass easily through cell membranes. In effect, orotate ferries the mineral atoms into cells and tissues, producing higher concentrations.
Nieper promoted orotates as treatments for nearly every ailment imaginable and was consequently ignored; most of his medical claims were never rigorously tested. But in certain applications — such as athletic performance — where his ideas have recently received scientific scrutiny, they have been found to work. Nieper may have been on the right track after all.
Dr. Nieper's theoretical explanations of the mechanisms behind his stunning success in the clinical application of sophisticated mineral transporters rely heavily on the concept of the fixed pore mechanism of active transport. The theory called fixed pore mechanism suggests that a carrier molecule, in this case Orotic Acid (B-13), is attached to the compound being transported. This research has lead to the creation of mineral chelates called orotic acid chelates, or orotates which offers a 20 fold increase in utilizing minerals.
Calcium orotate was used by Nieper to treat bone loss and pain due to inflammation or osteoporosis, high blood pressure, angina pectoris, multiple sclerosis, encephalitis, retinitis, hepatitis, arthritis, arteriosclerosis, phlebitis and colitis. In addition, it is very effective against psoriasis, a scaling skin disorder. The long-term clinical tolerance and overall value of calcium orotate is far superior to other therapeutic calcium substances and to the so-called immune depressors.
Calcium Orotate is one of the three mineral transporters that is the most active in providing treatment for bone decalcification. Has a pronounced anti-inflammatory effect on arthritis, arteriosclerosis, retinitis, encephalitis and phlebitis, psoriasis, high blood pressure, multiple sclerosis and colitis. It can be very effective in re-calcifying the bone tissue following extensive radiation treatment of cancerous bone lesions.
Calcium Orotate tablets have been beneficial in: Assisting with prevention of osteoporosis. Helping to avoid muscle cramps. Relieving the pain associated with disc problems. Maintaining strong bones & teeth. Keeping your heart beating regularly Alleviation of insomnia Helping the body metabolize iron Reduced Stress Increased alertness
We use Calcium Orotate along with the other orotates (magnesium, potassium, zinc and lithium) at Global Healing Center in a whole body, synergistic approach to eliminating disease. The results that we see using calcium orotate conclude that it is absorbed, transported and utilizied in the body better than any other form of calcium. It is time that the public knows the truth about calcium, its many benefits, why it is necessary and the best form available. Remember that he first step in getting healthy is always education and I believe that it is your right to know the truth about every hopeful treatment and prevention option available to you.

About The Author

Loretta Lanphier, ND, CCN, HHP is a Doctor of Naturopath, Certified Clinical Nutritionist and Holistic Health Practitioner in the Houston, TX area and Vice President of Global Healing Center, Inc. A teacher and educator, she counsels Global Healing Center clients on the aspects of getting the body healthy and keeping the body healthy. As a cancer survivor, she is able to relate extensively, both as a patient and a practitioner, to clients suffering from disease. She is also involved in researching new alternative disease treatments and products. Dr. Lanphier is Assistant Editor and contributor to the worldwide newsletter Alternative Health & Healing. ml

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Char4, what sort of side effects did you experience? Often 'salts' will attack soft tissue while penetrating bone. Did it affect your esophagus or stomach lining?

I was very interested in your posting.


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Hey juliemarie, Calcium Orotate contains Magnesium, gives me diarrhea, had some headaches, not real sure it is related to CO. But it is a listed side effect.
Had no other GI issues.

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Where do you get the Calcium Orotate? Is it in liquid or tablet form? Is that the name under which it is sold?

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Hey borobell, Calcium Orotate tablets are sold under that name and this is the website were I bought the last bottle:

There are a few other vendors.

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More on Calcium Orotate and Ezorb from GHC:
Calcium absorption takes place primarily in the small intestine, regardless of the source or type of the calcium. This is the area in which most nutrient absorption takes place. Both calcium orotate and aspartate are very good forms. Below is another post that offers some information on this subject:

Both of these forms of calcium are excellent and surpass almost all other forms of calcium on the market. Nieper was actually involved in the development of both the aspartate and the orotate carriers in the late 1950’s. Clinically, he actually used calcium orotate and sometimes Calcium 2-AEP for the treatment of osteoporosis and cartilage diseases. Obviously, he was very aware of the aspartate form and chose the orotate carrier instead. One reason for this is that orotate carriers have no affinity for the outer cell membrane and are instead delivered in to inside of a cell before they ionize and become available. Dr Neiper felt that “calcium orotate really performs clinical effects in various diseases connected with decalcification and injury of bones which can rapidly be improved by means of the application of calcium orotate by using this new concept of active mineral transport since we know, especially in studies run in Zurich, that all formation of bone, more or less, is controlled by cell membrane and that the microgranules of apatit have to be formed inside the osteoblast and then released through the cell membrane again.” Calcium aspartate is instead targeted more specifically to the inner layer of the outer membrane. As far as the percentages, Calcium aspartate yields approximately 13% elemental calcium and Calcium orotate yields between 10-11%; the 1.5 grams will yield about 150-165 mgs of calcium. Given the 90-95% absorption rate with this form, compared to 5-10% of calcium carbonate for instance, the low elemental percentage is more than compensated for in the higher absorption percentage, which is about 5-10% for Calcium Carbonate.

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